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Breast cancer and birth control study. Breast Cancer Risk and Prevention

But the importance of the increase is unique to each domain and depends on many factors, including: Hormonal Contraception ane Risk of Breast Path On December 7,a cohort study analyzing the risk of guest breast cancer in women who cabcer hormonal contraception was published in the New England Middle of Medicine 1. A Practice Advisory is issued when information on an emergent clinical path e. But the importance of the increase is unique to each are and depends on many factors, including: Hormonal Contraception and Risk of Breast After On December 7,a cohort study analyzing the risk of process breast cancer in women who used hormonal contraception was published in the New England Perforated of Medicine 1.

This type of birth control pill is often called a combined oral contraceptive. Another type of oral contraceptive, sometimes called the mini pill, contains only progestinwhich is a man-made version of progesterone. What is known about the relationship between oral contraceptive use and cancer? Risi all the caner on the link between oral contraceptives and cancer risk comes from observational studiesboth large prospective cohort studies and population-based case—control studies. Data from observational studies cannot definitively establish that an exposure—in this case, oral contraceptives—causes or prevents cancer. Overall, however, these studies have provided consistent evidence that the risks of breast and cervical cancers are increased in women who use oral contraceptives, whereas the risks of endometrialovarianand colorectal cancers are reduced 1 — 3.

An elevated risk associated with specific triphasic formulations was also reported in a nested case—control study that used electronic medical records to verify oral contraceptive use 7. Ina large prospective Danish study reported breast cancer risks associated with more recent formulations of oral contraceptives 8. The risk of breast cancer also increased the longer oral contraceptives were used. Relative risk increased with duration of use, ranging from 1.

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In general, risk was similar among different formulations or preparations of combined oral contraceptives. The results among progestin-only methods were inconsistent, with no statistically significant increased risk with some progestin-only methods but an increased risk with others, including oral levonorgestrel which is not marketed for contraception in the United States. Among women who used the levonorgestrel-releasing intrauterine device LNG-IUDthe relative risk of breast cancer was 1. Key Points This study found that the overall risk of breast cancer among hormonal contraceptive users is low.

Because of the low baseline risks in the age groups using hormonal contraception ie, premenopausal womenthe risk difference between hormonal contraception users and nonusers is small. The relationship between oral contraceptive use and breast cancer has been the subject of a number of studies. The increased relative risk observed in the current study translates into 1 additional case of invasive breast cancer for every 7, women using hormonal contraception 1. This risk varied with age: The relationship between progestin-only contraceptives and breast cancer risk warrants further study. The risks for different progestin-only formulations were inconsistent and dose-response and duration-response relationships were not present, making it very difficult to interpret these findings.

In this study, the LNG-IUD had a relative risk of breast cancer similar to that of combined hormonal oral contraception, whereas contraceptive implants and injectables had no observed increased risk. Methods with higher systemic levels of progestin, particularly injectables, did not Breast cancer and birth control study. Breast Cancer Risk and Prevention to be associated with increased risk. Hormonal contraception has other significant health benefits. The small increased risk of breast cancer identified Prrvention this study needs to be interpreted Breash the context of the benefits of hormonal contraceptive use.

Nad noncontraceptive benefits of hormonal contraception are well-established and include decreased risk of ovarian, endometrial, and colon cancer 4. Because of protection against these cancers, overall cancer risk may be slightly lower in hormonal contraceptive users compared with nonusers, even with the small increased breast cancer risk observed in this study 5. The benefits of hormonal contraceptives in preventing pregnancy are also important. There is evidence that hormonal contraceptives may increase the risk of the cancer coming back recurrence.

To do the study, the researchers looked at the medical records of all women living in Denmark between the ages of 15 and 49 as of Jan. They excluded women who: Because Denmark has national healthcare, the researchers were able to look up information on how many women used hormonal birth control and which type they used. They also looked up how many of the women were diagnosed with invasive breast cancer. During follow-up, 11, cases of breast cancer were diagnosed among the women. The researchers found that women who used hormonal contraceptives had a slightly higher risk of breast cancer than women who had never used hormonal contraceptives.


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